Why Ultra-Sensitive Drug Detection Matters at the Point of Care

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The opioid crisis continues to evolve, with increasingly potent and unpredictable substances fueling a rise in overdose deaths across the U.S. In this high-stakes environment, healthcare professionals, harm reduction teams, and first responders face pressure to detect and respond to synthetic opioids and novel adulterants with speed, precision, and confidence.

Yet many of today’s testing tools fall short.

The Growing Threat of Synthetic Adulterants

Fentanyl remains the leading cause of opioid-related overdose deaths, but it is no longer acting alone. Xylazine, a veterinary sedative, and nitazenes, a powerful class of synthetic opioids, are now frequently found as co-adulterants, often undetectable with standard field tests.

These substances are not only highly toxic, but they also complicate overdose reversal protocols. Xylazine, for example, is not an opioid and does not respond to naloxone. Identifying its presence early can change how clinicians manage airway protection, sedation, and patient monitoring.

Detection Gaps at the Front Lines

Most point-of-care drug tests are not equipped to detect these compounds at clinically relevant levels. Some require expensive instrumentation, while others offer low sensitivity and ambiguous results. This creates a dangerous delay in care, and potentially fatal misjudgments in the field.

That’s where high-sensitivity lateral flow diagnostics from Instanosis come in.

Precision That Saves Lives

Instanosis’ FXN 3-in-1 Test Kit detects fentanyl, xylazine, and nitazene simultaneously, with industry-leading sensitivity:

  • Fentanyl: Detects as low as 2 ng/mL
  • Xylazine: Detects as low as 10 ng/mL
  • Nitazene: Detects as low as 50 ng/mL

Results are delivered in under 5 minutes, enabling rapid clinical decision-making without lab infrastructure. The kit includes all tools for sample preparation and is engineered for use in hospitals, clinics, community settings, and law enforcement environments.

Designed for Today’s Overdose Landscape

Funded by the NIH and manufactured in the U.S., Instanosis tests are trusted by healthcare professionals seeking accuracy, simplicity, and speed. Whether used in emergency departments, detox centers, or outreach programs, the FXN 3-in-1 Kit empowers teams to:

  • Identify the true agents behind overdose events
  • Reduce time to appropriate care
  • Improve patient outcomes
  • Enhance compliance with screening protocols

Learn more about how Instanosis is advancing drug detection at the point of care. Visit www.instanosis.com or reach out to support@instanosis.com.